R306 Fleckvieh Haplotype 4 (FH4)
€ 39,95 ex. VAT
€ 48,34 inc. VAT
10
working days
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Abortion due to Fleckvieh Haplotype 4 (FH4) is an autosomal recessive disorder that occurs in Fleckvieh cattle. This causal mutation is located in the SUGT1 gene, which encodes for the protein SGT1. The protein SGT1 is part of the cell cycle and a deficiency in this protein will affect the progression of cell-cycle. A deficiency in this process causes early loss of embryos, resulting in reduced fertility of carrier cattle when mated together.
Specifications
Chromosome: 12
Gene: SUGT1
Mode of Inheritance: Autosomal Recessive Lethal
Also known as: FH4
Organ: Multiple systems
Species:Cattle
Year published: 2015
Clinical Features
Due to very early loss of affected embryos, pregnancy does not proceed further and the cow will directly enter the next estrous cyclus.
References
Omia: 1960
Pubmed: 25927203
