R330 Deficiency of Uridine Monophosphate Synthase (DUMPS)
€ 39,95 ex. VAT
€ 48,34 inc. VAT
Breed: Holstein
Sample material: Blood EDTA, Blood Heparin, Hair, Semen, Tissue
10
working days
For inquiries about our products or requests for larger volumes of DNA tests, please contact us.
Back to all DNA tests for cattle
Deficiency of Uridine Monophosphate Synthase (DUMPS) is a metabolic disease that results in the spontaneous abortion of affected calves in utero. The disorder is found primarily in the Holstein, and is caused by a recessive mutation to the UMPS gene.
Specifications
Chromosome: 1
Gene: UMPS
Mode of Inheritance: Autosomal Recessive
Also known as: DUMPS, HHD
Organ: Multiple systems
Species:Cattle
Year published: 1993
Clinical Features
Affected embryos are unable to produce an essential enzyme and die within approximately 40 days after fertilization, causing spontaneous abortion of the pregnancy. Carrier cattle appear normal and have no symptoms, but do have increased levels of orotic acid in their blood and tissue.
References
Omia: 262
Pubmed: 8486364
