R340 Bulldog Dwarfism (Chondrodysplasia) – Dexter

Bulldog Dwarfism (also known as Bulldog Calf Syndrome or Congenital Bovine Chondrodysplasia) is a severe developmental disorder in cattle which results in stillborn, misshapen calves. The disorder is caused by a recessive mutation to the gene ACAN, which affects cartilage development. We test for the BD1 variant of the disorder, which is primarily found in the Dexter breed. There is also a rarer variant, BD2, which results from a mutation in the same ACAN gene and was found in a particular bull lineage. VHLGenetics does not perform a test for this variant.