R360 Bovine Lymphocyte Intestinal Retention Defect (BLIRD)
€ 39,95 ex. VAT
€ 48,34 inc. VAT
10
working days
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Bovine Lymphocyte Intestinal Retention Defect (BLIRD) is a congenital immune disorder that causes stunted growth. It is found in Holstein cattle, particularly in the descendants of prolific bulls Elton and O-Man, to whom the disease has been traced. The disease is caused by a recessive mutation to the gene ITGB7.
BLIRD was first described in scientific literature in 2023, and the extent of its effects is still being researched.
Specifications
Chromosome: 5
Gene: ITGB7
Mode of Inheritance: Autosomal Recessive
Also known as: BLIRD
Organ: Digestive system
Sub-organ: Small intestine
Species:Cattle
Year published: 2023
Clinical Features
Affected cattle are unable to retain normal amounts of T-cells in the intestines. This results in an average of 27% reduced growth compared to healthy siblings, as well as abnormal white blood cell values. This can cause additional effects such as increased mortality in affected calves.
References
Omia: 2872
Pubmed: 39343954
