R520 Bovine Leukocyte Adhesion Deficiency (BLAD)
€ 39,95 ex. VAT
€ 48,34 inc. VAT
10
working days
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Bovine Leukocyte Adhesion Deficiency (BLAD) in calves is an autosomal recessive disorder. BLAD reduces the expression of certain proteins (Beta 2 integrin) on white blood cells. This reduced expression results in several defects of the function of the white blood cells and thus the imune system of these calves. The disorder is caused by a recessive mutation to the gene ITGB2.
BLAD is related to human LAD, and CLAD in dogs.
Specifications
Chromosome: 1
Gene: ITGB2
Mode of Inheritance: Autosomal Recessive
Also known as: BLAD, HHB
Organ: Cardiovascular system
Sub-organ: Blood
Species:Cattle
Year published: 1992
Clinical Features
Affected calves have a compromized immune system and are highly susceptible to (potentially lethal) infections.
References
Omia: 595
Pubmed: 1384046
