R534 Beta-Casein (A2 Genotyping)

R534 Categories: ,

 31,50 ex. VAT
 38,12 inc. VAT

Breed:  All Breeds
Sample material:  Blood EDTA, Blood Heparin, Hair, Semen, Tissue


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Cow’s milk contains six main proteins that affect its nutritional value: Alpha-casein S1 and S2, beta-casein, kappa-casein, alpha-lactalbumin and beta -actoglobulin. Various mutations to the genes responsible for forming these proteins can alter its nutritional properties, cheese-making potential, digestibility by human consumers, etc.

This test analyses a cow’s beta-casein for the highly desirable A2 genotype mutation, which is located on the gene CSN2.


Chromosome: 6

Gene: CSN2

Mode of Inheritance: Autosomal Co-Dominant

Organ: Endocrine glands

Sub-organ: Mammary glands


Year published: 2013

Clinical Features

Cows will produce milk containing the a mixture of the beta casein variants they carry. For example, a cow genotyped as A2/A2 will produce pure A2 milk, and a cow genotyped as A1/A2 will produce A1 and A2 beta-casein in its milk.

Additional information

This test cannot distinguish between the mutations for beta-casein A2, H2 and I. The advanced test is required for that.


Omia: 2033

Pubmed: 23102962