R550 Complex Vertebral Malformation (CVM)
€ 39,95 ex. VAT
€ 48,34 inc. VAT
10
working days
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Complex Vertebral Malformation (CVM) is a hereditary disorder found primarily in Holstein cattle. It is a skeletal development disorder which can result in malformed, stillborn calves or in spontaneous pregnancy abortions. It is caused by a recessive mutation to the gene SLC35A3.
The disorder has spread considerably through cattle populations worldwide due to the extensive use of elite bulls carrying the mutation.
Specifications
Chromosome: 3
Gene: SLC35A3
Mode of Inheritance: Autosomal Recessive
Also known as: CVM, HHC
Organ: Skeletal system
Sub-organ: Vertebral column
Species:Cattle
Year published: 2006
Clinical Features
Affected calves are physically malformed and likely to be stillborn, and euthanasia is likely required for surviving calves on humane and/or livestock management grounds. Typical signs of CVM include a shortened neck, protruding tongue, misshapen head and hernias of the abdomen. Pregnancies carrying affected calves may also spontaneously abort.
References
Omia: 1340
Pubmed: 16344554
