R851 Factor XI Deficiency (FXID)

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 39,95 ex. VAT
 48,34 inc. VAT

Breed:  Holstein, Sahiwal
Sample material:  Blood EDTA, Blood Heparin, Hair, Semen, Tissue


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Factor XI Deficiency (FXID) is a disorder that affects blood clotting, which can lead to abnormal, excessive bleeding. The disease is caused by a recessive mutation to the gene F11, and is found primarily in the Holstein cow.


Chromosome: 27

Gene: F11

Mode of Inheritance: Autosomal Recessive

Also known as: FXID

Organ: Cardiovascular system

Sub-organ: Blood


Year published: 2004

Clinical Features

Affected cattle may display a wide range of bleeding abnormalities, including continued bleeding from the umbilical cord in calves, prolonged bleeding after dehorning or castration, and bloody milk. Both carriers and affected cattle may additionally have poorer reproductive performance and an increased vulnerability to infectious diseases.


Omia: 363

Pubmed: 15566468