S309 Resistance to Ovine Progressive Pneumonia (OPP Resistance)

S309 Categories: ,

 39,95 ex. VAT
 48,34 inc. VAT

Breed:  All Breeds
Also known as:  MV


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Ovine progressive pneumonia (OPP), or maedi-visna, is a chronic disease of sheep due to lentiviruses. The virus has a long incubation time and high mortality rate, and no effective vaccine or treatment against it currently exists. However, some sheep have been found to have genetic resistance against the disease, which can dramatically improve survival rates. The test offered here is for a variant of the gene TMEM154. Sheep homozygous for this variant, which can found among all breeds, have been demonstrated to be less susceptible to infection.

The related disease in goats is referred to as caprine arthritis and encephalitis (CAE).

Additional information

Also known as




Mode of Inheritance



Year Published


Chromosome: 17

Gene: TMEM154

Mode of Inheritance: Multifactorial

Organ: Multiple systems


Year published: 2012

Clinical Features

Resistant sheep are less likely to catch OPP, and will recover from it faster.


Omia: 1694

Pubmed: 22291605