V579 Rendement Napole Gene (RN)

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Breed:  All Breeds
Sample material:  Blood EDTA, Blood Heparin, Hair, Semen, Tissue


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The gene PRGAK3 is associated with muscle glycogen content and meat quality. In pigs, a variant of this gene is known as the Rendement Napole (RN) gen or allele.

Carriers of this dominant mutation show lower muscle pH 24 hr after slaughter, reduced water-holding capacity in the muscle, and much lower yield of a cured cooked ham product due to an increase in muscle glycogen content. Carriers, on the other hand, have meat that is easier to cut, with a stronger taste and smell and greater acidity.


Chromosome: 15

Gene: PRKAG3

Mode of Inheritance: Autosomal Dominant

Also known as: RN

Organ: Muscles

Sub-organ: Whole muscular system


Year published: 2000

Clinical Features

The change of amino acid at this location on the PRKAG3 gene is involved in glucose metabolism and therefore the muscle glycogen content.

Additional information

Meat quality is based on many factors. It is influenced by postmortem tenderization, which is a complex structural and functional process that depends on species, genetic background, metabolic status of the animal antemortem, the protein complement of the muscle, and environmental factors.


Omia: 1085

Pubmed: 10818001